What’s the medical relevance of vitamin C amongst lead-exposed infertile males? In comparison with controls, lead battery trade staff given 1,000 mg of vitamin C each workday for 3 months skilled “a big improve in sperm motility and sperm depend, in addition to lower in irregular sperm,” and “a big discount within the incidence of sperm DNA fragmentation,” that’s, broken sperm DNA. Okay, however the splendid endpoint could be bouncing child girls and boys. Enter this extraordinary little research from the College of Texas from greater than 30 years in the past.
Twenty-seven males with fertile wives had been attempting to have youngsters for years to no avail. Twenty of them got 1,000 mg of vitamin C a day for 2 months, and seven acted as controls and didn’t get any vitamin C. The researchers adopted up on the finish of the 60 days. By then, each single one of many wives of every of the 20 males who had gotten the vitamin C had turned pregnant—20 out of 20! After years of frustration, growth: 100-percent pregnant. What’s extra, not a single one of many wives of males within the management group obtained pregnant. Not often does one see these sorts of black-and-white leads to the medical literature for any intervention.
Is the vitamin C reducing the oxidative stress from the lead, or is it truly reducing the degree of lead? Certain, antioxidant supplementation can have antioxidant results, however it could fail to really decrease lead ranges within the blood. Now, this was in a body of workers who had been respiratory lead day in and time out, and the best way vitamin C may fit is by merely blocking the “intestinal absorption of lead.” An earlier research confirmed vitamin C supplementation apparently minimize lead ranges by a 3rd inside six months, however that was with a whopping dose of two g with added zinc. One other small research discovered the identical 30 p.c drop with simply 500 mg a day, no zinc, and in just one month. However neither of these research had a management group of topics who didn’t take something, so we don’t know if their ranges would have fallen anyway.
Equally, there’s an virtually too-good-to-be-true research on the position of vitamin C in scavenging lead toxicity from “biosystems,” by which they meant kids. They obtained 250 to 500 mg a day of vitamin C for just a few months, and shaved hair samples each month noticed as much as a 69 p.c decline in lead ranges. Researchers repeated it in two different small teams of children and noticed the identical superb sort of drops in each single baby. However perhaps lead ranges had been simply dropping all through the entire neighborhood throughout that point? With out measuring lead ranges in a management group of children not taking vitamin C, we will’t ensure.
As I illustrate from 3:17 in my video Yellow Bell Peppers for Male Infertility and Lead Poisoning?, with eight weeks of vitamin C, lead ranges dropped within the blood and rose within the urine. One may conclude that the vitamin C was pulling lead out of the physique, however the identical factor occurred within the placebo group: Blood ranges dropped, and urine ranges rose. So, it had nothing to do with the vitamin C in any respect. That’s why it’s all the time necessary to have a management group.
The identical applies with research that appeared to point out no profit. For instance, 36 battery manufacturing staff had been studied. Every was given vitamin C, but there was no change of their lead ranges. However, perhaps their co-workers suffered a giant improve in lead ranges throughout that very same time interval, and the vitamin C was truly profitable in preserving the topics’ ranges from rising. You don’t know with out a management group.
That’s why research like “The consequences of vitamin C supplementation on blood and hair ranges of cadmium, lead, and mercury” are so necessary. Vitamin C versus an identical-looking sugar capsule placebo. The outcome? The vitamin C failed to assist, which actually put a damper on enthusiasm for utilizing vitamin C for lead poisoning till a now-famous research was printed in 1999 that confirmed that vitamin C supplementation may result in a lower in blood ranges. As you’ll be able to see at 4:32 in my video, after 4 weeks of taking a placebo, not a lot change occurred in blood lead ranges within the management group, which is what we’d count on. In distinction, the vitamin C group began out at about the identical blood lead degree because the management group, however inside one week of taking 1,000 mg of vitamin C a day, lead ranges dropped 81 p.c. So, supplementation of vitamin C “could present a cost-effective and handy technique of decreasing blood-lead ranges, probably by decreasing the intestinal absorption of lead.”
The urine lead ranges didn’t change, so it’s not as if the topics had been excreting extra lead of their urine to deliver down their blood ranges. Nevertheless, many of the lead in our blood is within the purple blood cells, that are recycled within the liver and discharged by way of the bile into the intestine the place the lead may simply get reabsorbed—except, maybe, you’ve obtained numerous vitamin C in there to dam the re-absorption. However 1,000 mg is numerous vitamin C. Would one thing like 200 mg, which is nearly how a lot vitamin C you’d get in an orange and a cup of broccoli or strawberries, work? The researchers examined that, too. The 200 mg group began out the identical because the management and the 1,000 mg group, however blood lead ranges didn’t actually budge. Bummer! So, 1,000 mg appeared to work, however 200 mg didn’t. Isn’t 1,000 mg of vitamin C a bit unnatural, although? The RDA is just 60 mg. Properly, truly, we could have advanced for hundreds of thousands of years getting nearer to 600 mg a day—ten instances the present RDA—as a result of we had been consuming so many fruits and greens. Okay, however may you attain 1,000 mg of vitamin C with out having to take tablets? Sure! That’s the quantity of vitamin C, for instance, that may be present in three yellow bell peppers.
Different movies in my collection on lead embody:
- Is Lipstick Protected Given the Lead Contamination?
- Can Saunas Detoxify Lead from the Physique?
- How the Lead Paint Trade Received Away with It
- Lead in Ingesting Water
- How the Leaded Fuel Trade Received Away with It
- “Regular” Blood Lead Ranges Can Be Poisonous
- The Results of Low-Degree Lead Publicity in Adults
- Methods to Decrease Lead Ranges with Food plan: Thiamine, Fiber, Iron, Fats, Fasting?
- Methods to Decrease Lead Ranges with Food plan: Breakfast, Entire Grains, Milk, Tofu?
- Finest Meals for Lead Poisoning: Chlorella, Cilantro, Tomatoes, Moringa?
- Finest Meals for Lead Poisoning: Garlic
- Can Vitamin C Assist with Lead Poisoning?
- How A lot Lead Is in Natural Rooster Soup (Bone Broth)?
- Lead in Calcium Dietary supplements
- Ought to Pregnant Ladies Take Calcium Dietary supplements to Decrease Lead Ranges?
- The Rise in Blood Lead Ranges at Being pregnant and Menopause
- Lead Contamination in Fish and Recreation
- Lead Contamination in Sizzling Sauces
Notice that there’s nothing particular about yellow bell peppers—apart from their extraordinary vitamin C content material, that’s. I simply used them as a sensible solution to get 1,000 mg of vitamin C in whole-food type. They’re definitely simpler than consuming ten oranges!
Although, bear in mind my video Peppers and Parkinson’s: The Advantages of Smoking With out the Dangers? So, one would count on to get all the advantages of the 1,000 mg of vitamin C with advantages. Why not simply take vitamin C dietary supplements? See Do Vitamin C Dietary supplements Forestall Colds however Trigger Kidney Stones?.
If tons of of milligrams a day of vitamin C seems like quite a bit, try What Is the Optimum Vitamin C consumption?.
It’s possible you’ll be eager about my vitamin C and most cancers collection:
Lastly, for extra on male fertility, see:
In well being,
Michael Greger, M.D.
PS: In the event you haven’t but, you’ll be able to subscribe to my free movies right here and watch my dwell displays: